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From boiling thermal hot springs to deep beneath the Antarctic ice, microorganisms can be found almost everywhere on earth in great quantities. Microorganisms (or microbes, as they are also called) are small organisms. Most are so small that they cannot be seen without a microscope.

Most microorganisms are harmless to humans and, in fact, many are helpful. They play fundamental roles in ecosystems everywhere on earth, forming the backbone of many food webs. People use them to make biofuels, medicines, and even foods. Without microbes, there would be no bread, cheese, or beer. Our bodies are filled with microbes, and our skin alone is home to trillions of them. Some of them we can’t live without; others cause diseases that can make us sick or even kill us.

Although much more is known today about microbial life than ever before, the vast majority of this invisible world remains unexplored. Microbiologists continue to identify new ways that microbes benefit and threaten humans.


“Source: OpenStax College, Microbiology. OpenStax CNX | Download for free at Download for free at https://cnx.org/contents/[email protected]

Course Curriculum

Preface
Preface – Microbiology Foundation 00:30:00
1. An Invisible World
Introduction – An Invisible World 01:00:00
What Our Ancestors Knew 01:30:00
A Systematic Approach 01:30:00
Types of Microorganisms 01:30:00
Microbio Ch1 Quiz 00:10:00
2. How We See the Invisible World
Introduction – How We See the Invisible World 01:00:00
The Properties of Light 01:30:00
Peering Into the Invisible World 01:30:00
Instruments of Microscopy 01:30:00
Staining Microscopic Specimens 01:30:00
MicroBio Ch2 Quiz 00:10:00
3. The Cell
Introduction – The CellFREE 01:30:00
Spontaneous Generation 01:30:00
Foundations of Modern Cell Theory 01:30:00
Unique Characteristics of Prokaryotic Cells 01:30:00
Unique Characteristics of Eukaryotic Cells 01:30:00
4. Prokaryotic Diversity
Introduction – Prokaryotic Diversity 01:00:00
Prokaryote Habitats, Relationships, and Microbiomes 01:30:00
Proteobacteria 01:30:00
Nonproteobacteria Gram-Negative Bacteria and Phototrophic Bacteria 01:30:00
Gram-Positive Bacteria 01:30:00
Deeply Branching Bacteria 01:30:00
Archaea 01:30:00
5. The Eukaryotes of Microbiology
Introduction – The Eukaryotes of Microbiology 01:30:00
Unicellular Eukaryotic Parasites 01:30:00
Parasitic Helminths 01:30:00
Fungi 01:30:00
Algae 01:30:00
Lichens 01:30:00
6. Acellular Pathogens
Introduction – Acellular Pathogens 01:00:00
Viruses 01:30:00
The Viral Life Cycle 01:30:00
Isolation, Culture, and Identification of Viruses 01:30:00
Viroids, Virusoids, and Prions 01:30:00
7. Microbial Biochemistry
Introduction – Microbial Biochemistry 01:30:00
Organic Molecules 01:30:00
Carbohydrates 01:30:00
Lipids 01:30:00
Proteins 01:30:00
Using Biochemistry to Identify Microorganisms 01:30:00
8. Microbial Metabolism
Introduction – Microbial Metabolism 01:30:00
Energy, Matter, and Enzymes 01:30:00
Catabolism of Carbohydrates 01:30:00
Cellular Respiration 01:30:00
Fermentation 01:30:00
Catabolism of Lipids and Proteins 01:30:00
Photosynthesis 01:30:00
Biogeochemical Cycles 01:30:00
9. Microbial Growth
Introduction – Microbial Growth 01:30:00
How Microbes GrowFREE 01:30:00
Oxygen Requirements for Microbial Growth 01:30:00
The Effects of pH on Microbial Growth 01:30:00
Temperature and Microbial Growth 01:30:00
Other Environmental Conditions that Affect Growth 01:30:00
Media Used for Bacterial Growth 01:30:00
10. Biochemistry of the Genome
Introduction – Biochemistry of the Genome 01:30:00
Using Microbiology to Discover the Secrets of Life 01:30:00
Structure and Function of DNA 01:30:00
Structure and Function of RNA 01:30:00
Structure and Function of Cellular Genomes 01:30:00
11. Mechanisms of Microbial Genetics
Introduction – Mechanisms of Microbial Genetics 01:30:00
The Functions of Genetic Material 01:30:00
DNA Replication 01:30:00
RNA Transcription 01:30:00
Protein Synthesis (Translation) 01:30:00
Mutations 01:30:00
How Asexual Prokaryotes Achieve Genetic Diversity 01:30:00
Gene Regulation: Operon Theory 01:30:00
12. Modern Applications of Microbial Genetics
Introduction – Modern Applications of Microbial Genetics 01:30:00
Microbes and the Tools of Genetic Engineering 01:30:00
Visualizing and Characterizing DNA, RNA, and Protein 01:30:00
Whole Genome Methods and Pharmaceutical Applications of Genetic Engineering 01:30:00
Gene Therapy 01:30:00
13. Control of Microbial Growth
Introduction – Control of Microbial Growth 01:30:00
Controlling Microbial Growth 01:30:00
Using Physical Methods to Control Microorganisms 01:30:00
Using Chemicals to Control Microorganisms 01:30:00
Testing the Effectiveness of Antiseptics and Disinfectants 01:30:00
14. Antimicrobial Drugs
Introduction – Antimicrobial Drugs 01:30:00
History of Chemotherapy and Antimicrobial Discovery 01:30:00
Fundamentals of Antimicrobial Chemotherapy 01:30:00
Mechanisms of Antibacterial Drugs 01:30:00
Mechanisms of Other Antimicrobial Drugs 01:30:00
Drug Resistance 01:30:00
Testing the Effectiveness of Antimicrobials 01:30:00
15. Microbial Mechanisms of Pathogenicity
Introduction – Microbial Mechanisms of Pathogenicity 01:30:00
Characteristics of Infectious Disease 01:30:00
How Pathogens Cause Disease 01:30:00
Virulence Factors of Bacterial and Viral Pathogens 01:00:00
Virulence Factors of Eukaryotic Pathogens 01:30:00
16. Disease and Epidemiology
Introduction – Disease and Epidemiology 01:00:00
The Language of Epidemiologists 01:00:00
Tracking Infectious Diseases 00:00:00
Modes of Disease Transmission 01:00:00
Global Public Health 01:00:00
17. Innate Nonspecific Host Defenses
Introduction – Innate Nonspecific Host DefensesFREE 01:00:00
Physical Defenses 00:00:00
Chemical Defenses 01:00:00
Cellular Defenses 01:00:00
Pathogen Recognition and Phagocytosis 01:00:00
Inflammation and Fever 00:00:00
18. Adaptive Specific Host Defenses
Introduction – Adaptive Specific Host Defenses 01:00:00
Overview of Specific Adaptive Immunity 01:00:00
Major Histocompatibility Complexes and Antigen-Presenting Cells 01:00:00
T Lymphocytes and Cellular Immunity 01:00:00
B Lymphocytes and Humoral ImmunityFREE 01:00:00
VaccinesFREE 01:00:00
19. Diseases of the Immune System
Introduction – Diseases of the Immune System 01:00:00
Hypersensitivities 00:00:00
Autoimmune Disorders 01:00:00
Organ Transplantation and Rejection 01:00:00
Immunodeficiency 01:00:00
Cancer Immunobiology and Immunotherapy 01:00:00
20. Laboratory Analysis of the Immune Response
Introduction – Laboratory Analysis of the Immune Response 01:00:00
Polyclonal and Monoclonal Antibody Production 01:00:00
Detecting Antigen-Antibody Complexes 01:00:00
Agglutination Assays 01:00:00
EIAs and ELISAs 01:00:00
Fluorescent Antibody Techniques 01:00:00
21. Skin and Eye Infections
Introduction – Skin and Eye Infections 01:00:00
Anatomy and Normal Microbiota of the Skin and Eyes 00:00:00
Bacterial Infections of the Skin and Eyes 01:00:00
Viral Infections of the Skin and Eyes 01:00:00
Mycoses of the Skin 01:00:00
Protozoan and Helminthic Infections of the Skin and Eyes 01:00:00
22. Respiratory System Infections
Introduction – Respiratory System Infections 01:00:00
Anatomy and Normal Microbiota of the Respiratory Tract 01:00:00
Bacterial Infections of the Respiratory Tract 01:00:00
Viral Infections of the Respiratory Tract 01:00:00
Respiratory Mycoses 01:00:00
23. Urogenital System Infections
Introduction – Urogenital System Infections 01:00:00
Anatomy and Normal Microbiota of the Urogenital Tract 01:00:00
Bacterial Infections of the Urinary System 01:00:00
Bacterial Infections of the Reproductive System 01:00:00
Viral Infections of the Reproductive System 01:00:00
Fungal Infections of the Reproductive System 01:00:00
Protozoan Infections of the Urogenital System 01:00:00
24. Digestive System Infections
Introduction – Digestive System Infections 01:00:00
Anatomy and Normal Microbiota of the Digestive System 01:00:00
Microbial Diseases of the Mouth and Oral Cavity 01:00:00
Bacterial Infections of the Gastrointestinal Tract 01:00:00
Viral Infections of the Gastrointestinal Tract 01:00:00
Protozoan Infections of the Gastrointestinal Tract 00:00:00
Helminthic Infections of the Gastrointestinal Tract 01:00:00
25. Circulatory and Lymphatic System Infections
Introduction – Circulatory and Lymphatic System Infections 00:00:00
Anatomy of the Circulatory and Lymphatic Systems 01:00:00
Bacterial Infections of the Circulatory and Lymphatic Systems 01:00:00
Viral Infections of the Circulatory and Lymphatic Systems 01:00:00
Parasitic Infections of the Circulatory and Lymphatic Systems 00:00:00
26. Nervous System Infections
Introduction – Nervous System Infections 01:00:00
Anatomy of the Nervous System 01:00:00
Bacterial Diseases of the Nervous System 01:00:00
Acellular Diseases of the Nervous System 01:00:00
Fungal and Parasitic Diseases of the Nervous System 01:00:00
Appendix A
Fundamentals of Physics and Chemistry Important to Microbiology 01:00:00
Appendix B
Mathematical Basics 01:00:00
Appendix C
Metabolic Pathways 01:00:00
Appendix D
Taxonomy of Clinically Relevant Microorganisms 01:00:00
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